A study of pharmacognostic profile and antifungal activity of ethanolic extract of kapok banana weevil (Musa balbisiana)
Department of Pharmacy, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.
Research Article
International Journal of Scientific Research Updates, 2023, 06(01), 033–039.
Article DOI: 10.53430/ijsru.2023.6.1.0058
Publication history:
Received on 24 June 2023; revised on 05 August 2023; accepted on 08 August 2023
Abstract:
Dandruff is an anomaly on the scalp caused by Pityrosporum ovale. Dandruff-treated Ketoconazole shampoo, Excessive caused dermatitis and hair damage. The problem was solved using the kapok banana weevil as an alternative treatment. This study aims to determine the quality of kapok banana weevil simplicia and its anti-functional activity against P. ovale. The study was conducted in two stages, the first of which involved Pharmacognostic profiles on macroscopy, microscopy, Simplicia quality, and phytochemical screening. Examining the inhibitory zones of the ethanolic extract of P. ovale at doses of 0.5%, 1%, 2%, 4%, 5%, 10%, 20%, and 40% reveals stage 2 antifungal activity. Employing the Kirby-Bauer diffusion as a positive control with ketoconazole and a negative control with sterile aqua dest. A 95% confidence level LSD post hoc test, one-way ANOVA, and description technique were used to evaluate the data. Results: The Kapuk banana weevil's Simplisia met high standards for Simplisia quality, and its ethanol extract was able to stop P. ovale growth by creating an inhibition zone. The ethanol extract of the Kapuk banana weevil was able to suppress the development of P. ovale with an inhibition zone extending from 0.5 to 17.16 mm and positive control (ketoconazole) of 23.5 mm. The Simplisia of the Kapuk banana weevil had good simplicia quality standards. Extract with concentration of 40%and a 17.16 mm inhibition zone, the activity was at its peak. The pharmacognostic profile demonstrates the high quality of Simplicia, and the activities of the kapok banana weevil extract are at their peak at a concentration of 40% at a diameter of 17.16 mm.
Keywords:
Banana kapok; Pityrosporum ovale; Anti-fungal; Extract; Simplicia
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