Probiotic as supplementary therapy for chronic rhinosinusitis
1 Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
2 Department of Pharmacology and Therapeutic, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Review
International Journal of Scientific Research Updates, 2022, 04(01), 103–107.
Article DOI: 10.53430/ijsru.2022.4.1.0085
Publication history:
Received on 11 June 2022; revised on 18 July 2022; accepted on 20 July 2022
Abstract:
Chronic Rhinosinusitis is an inflammation in paranasal sinus and nasal cavity that can last up to a minimum of 12 weeks with prevalence 1% to 12% globally. The etiology of chronic rhinosinusitis is usually caused by combination of various factors such as pathogenic organism and obstruction of the sinus tract. The latest study also found imbalance in natural microbiome can cause chronic rhinosinusitis. One of the alternative therapies to help alleviate chronic rhinosinusitis is using probiotic. Probiotic is a living microorganism that, if given in adequate dosage, will provide health benefits for the host by keeping the balance of microbiome or commensal bacteria count in the body. Some latest studies showed the efficacy of probiotic in rhinitis allergy, atopic prevention such as eczema, asthma, diarrhea and food allergy. Aim of this narrative review is to understand the efficacy of probiotic and possible side effects that might occur in the use of probiotics as supplementary therapy on chronic rhinosinusitis.
Keywords:
Chronic rhinosinusitis; Probiotic; Microbiome; Immune system; Sinus cavity; Commensal bacteria
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