LC-MS analysis and free radical scavenging activity of extracts from Anogeissus leiocarpus (DC.) Guill. & Perr. and Sansiviera liberica Gerome & Labroy
1 Department of Chemistry, University of Ibadan, Nigeria.
2 Veterinary Microbiology and Parasitology, University of Ibadan, Nigeria.
3 Department of Chemistry and Chemical Biology, Institute of Environmental Research (INFU), TU Dortmund University, Dortmund Germany.
Research Article
International Journal of Scientific Research Updates, 2022, 04(01), 244–249.
Article DOI: 10.53430/ijsru.2022.4.1.0060
Publication history:
Received on 22 May 2022; revised on 04 July 2022; accepted on 06 July 2022
Abstract:
Anogeissus leiocarpus and Sansiviera liberica are plants used in traditional medicine as antiviral agents. A preliminary study of the bioactive constituents was carried out using Liquid Chromatography – Mass Spectrometry (LC-MS) technique. Free radical scavenging activity of the crude extracts were determined using 2,2-diphenyl picrylhydrazyl radical method. Results obtained showed that Anogeissus leiocarpus and Sansiviera liberica were rich in alkaloids and their glycosides. Methanol extract of stem of Anogeissus leiocarpus (MSAL) at 1.0 mg/mL was more active than methanol extract of the twig of Sansevieria liberica (MTSL) with %inhibition of 79.5% and 78.1% respectively in the free radical scavenging assay. These activities were significant when compared with butylated hydroxylanisole and ascorbic acid. This study has given a clue to the traditional application of these two plants as antiviral agents in ethnomedicine.
Keywords:
Anogeissus leiocarpus; Sansiviera liberica; Free Radicals; Alkaloids; Glycosides; LC-MS
Full text article in PDF:
Copyright information:
Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0