Chronic heart failure and COVID-19

Nasirova G. A * and Mukhamedova M. G

Center for the development of professional qualification of medical workers, Tashkent, Uzbekistan.
 
Review
International Journal of Scientific Research Updates, 2023, 05(01), 138–142.
Article DOI: 10.53430/ijsru.2023.5.1.0023
Publication history: 
Received on 10 January 2023; revised on 18 February 2023; accepted on 21 February 2023
 
Abstract: 
The coronavirus pandemic has caused a rapid increase in the number of cases and high deaths worldwide. A new coronavirus infection in the presence of an initial cardiac pathology can provoke decompensation of chronic heart failure. The article shows current information on the pathogenesis of COVID-19 and organ-specific lesions that develop in this disease is presented. Data on inflammation and its biochemical markers, on the features of coagulopathy, endothelial damage and microthromboses has been reflected in detail in this article. Particular attention is paid to the role of type 2 angiotensin-converting enzyme receptors and type 2 transmembrane serine protease in the development of organ-specific lesions in COVID-19. The pathogenesis of damage to the cardiovascular system is considered in detail with the presentation of data from latest literature on changes in the myocardium in patients who underwent COVID-19.
 
Keywords: 
Chronic heart failure; COVID-19; Cardiovascular disease; Uzbekistan
 
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