Antibiogram of Klebsiella pneumoniae among population with community acquired urinary tract infection in Enugu State, Nigeria
1 Department of Medical Laboratory Science, Enugu State University of Science and Technology College of Medicine, Enugu, Nigeria.
2 Department of Medical Laboratory Science, University of Nigeria, Enugu Campus, Nigeria.
3 Department of Obstetrics & Gynaecoclogy, Enugu State University of Science and Technology College of Medicine/Teaching Hospital, Parklane, Enugu, Nigeria.
Research Article
International Journal of Scientific Research Updates, 2022, 04(01), 195–203.
Article DOI: 10.53430/ijsru.2022.4.1.0105
Publication history:
Received on 01 July 2022; revised on 14 August 2022; accepted on 16 August 2022
Abstract:
Antibiotic resistance possesses a serious challenge in the treatment of Urinary Tract Infections (UTIs). This study was therefore designed to determine the antibiogram of K. pneumoniae isolated from individuals presenting with UTIs in communities within Enugu state. A cross-sectional study was conducted from February, 2021 to June, 2021 and a total of 735 patients with community-acquired UTIs in Enugu state, Nigeria, were involved in the study. The patients were assessed clinically and microbiologically for Klebsiella pnuemoniae and antibiogram of the isolates were investigated. Out of 77 isolates of Klebsiella pneumaniae obtained, 29 (37.7%) showed multiple resistant to the antibiotics used, whereas 48 (62.3%) were either susceptible or intermediate. Of all the antibiotics tested, meropenem showed the highest recorded sensitivity to the test organism 63(19.93%), whereas the least sensitivity was observed in co-amoxiclav 11 (3.48%). Antibiogram of urinary K. pneumoniae isolated from rural dwellers showed a significantly high resistance to commonly used antibiotics; thus, the need for regular awareness campaign and antimicrobial resistance surveillance to increase knowledge, improve infection control measures, and check abuse of antibiotics.
Keywords:
Community-acquired UTI; Antibiotics; susceptibility; Resistance; Klebsiella pneumoniae
Full text article in PDF:
Copyright information:
Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0