Primary Carcinosarcoma of the breast: Report a very rare case
1 Department of Thoracic Surgery, Guilan University of Medical Sciences, Iran.
2 Department of Pathology, Guilan University of Medical Sciences, Iran.
3 Department of oncologisy, Guilan University of Medical Sciences, Iran.
4 Inflammatory Lung Diseases Research Center, Department of Internal Medicine, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Research Article
International Journal of Multidisciplinary Research Updates, 2024, 07(02), 012–018.
Article DOI: 10.53430/ijmru.2024.7.2.0028
Publication history:
Received on 09 February 2024; revised on 22 March 2024; accepted on 25 March 2024
Abstract:
Background: Sarcoma of the breast is a rare malignancy with heterogeneous histology. angiosarcoma is the most common type of sarcoma of the breast secondary from previous radiation.There is limited clinical and survival information from other types of breast sarcomas.
Case Presentation: Here we present A 56-year-old woman which presented with a mass in her right breast. On examination the tumor was not fixed to chest wall. But skin over mass was erymatous and with nipple retraction.A cor-needle biopsy was performed which showed leiomyosarcoma. After IHC the difintive diagnos was sarcoma. A radical resection of mass with radical mastectomy and axillary dissection were performed, in permanent pathology all margins was free of tumor. After surgery patient refer to radio oncologist for irradiation therapy
Conclusions: Surgical resection seems to be the most important treatment modality in sarcoma of the breast. Radiation therapy added a minor survival benefit to the patients who received surgical resection. Systemic chemotherapy did not any role in sarcoma of the breast.
Keywords:
Sarcoma; histology; Carcinosarcoma; Breast cancer; Primary Carcinosarcoma
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