Complement cascade and humoral-IgE skin cream
Alleam-it Corporation, Minnesota and USA.
Review
International Journal of Multidisciplinary Research Updates, 2022, 03(02), 037–039.
Article DOI: 10.53430/ijmru.2022.3.2.0060
Publication history:
Received on 06 October 2022; revised on 12 November 2022; accepted on 15 November 2022
Abstract:
During acute infection, antibodies establish the strength or weakness of the immune response. The body’s immunoglobulin signature may affect the complement cascade (innate immunity) and pro-inflammatory response. The review discusses immunoglobulin E (IgE) and its effect on the complement cascade. Specifically, the expression of IgE may affect complement cascade immunopathology. More specifically, IgE expression may inhibit the degranulation of mast cells and basophils by anaphylatoxins. Research explores if humoral-IgE skin cream therapy can reduce morbidity and mortality during acute infection.
Keywords:
Complement; Cytokine; IgE; Infection; Mast Cells; Skin Cream
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0